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Notice of NIAMS-specific language in RFA-NR-25-003 “Transformative Research to Address Health Disparities and Advance Health Equity (U01 Clinical Trial Optional)”

The purpose of this Notice is to add NIAMS-specific language in RFA-NR-25-003 “Transformative Research to Address Health Disparities and Advance Health Equity (U01 Clinical Trial Optional)”. The following updates have been made to RFA-NR-25-003 (shown in bold italics) to reflect NIAMS’ participation in this NOFO.

The following section of RFA-NR-25-003 has been revised:

Part 2. Section I. Notice of Funding Opportunity Description

Areas of Interest of Participating Institutes, Centers, and Offices (ICOs)

National Institute of Environmental Health Sciences (NIEHS)

NIEHS’ mission is to discover how the environment affects people in order to promote healthier lives and has long worked to reduce environmental health disparities and promote environmental justice. NIEHS is interested in innovative intervention research that addresses the interaction of SDOH with chemical

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Notice of Intent to Publish a Notice of Funding Opportunity for the Re-issue of RFA-AG-23-016 – Transition to Aging Research for Predoctoral Students (F99/K00 – Clinical Trial Not Allowed)

Notice Number:

NOT-AG-24-072

Key Dates

Release Date:

January 21, 2025

Estimated Publication Date of Notice of Funding Opportunity :

April 30, 2025

First Estimated Application Due Date:

September 17, 2025

Earliest Estimated Award Date:

June 17, 2026

Earliest Estimated Start Date:

June 17, 2026

Related Announcements

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Notice of Special Interest (NOSI): Digital Technology for Early Detection and Monitoring of Alzheimer’s Disease (AD) and AD-Related Dementias (ADRD)

This Notice of Special Interest (NOSI) encourages research on the use of digital technology for early detection and monitoring of cognitive and functional decline in persons with Alzheimer’s disease (AD) and AD-related dementias (ADRD). This NOSI is a reissue of NOT-AG-21-048.

Background

Early diagnosis and monitoring of AD/ADRD is an unmet need and a major goal in the Department of Health and Human Services’ National Plan to Address Alzheimer’s Disease. There is evidence that the functional, psychological, pathological, and physiological changes underlying AD/ADRD may emerge many years prior to the clinical manifestation of cognitive symptoms, prompting this call to identify earlier indicators of disease risk and subclinical disease burden.

Many current biomarkers for early detection of prodromal AD/ADRD (e.g., PET/MRI imaging)

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