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Notice of Correction to PAR-25-153 “Assay development and screening for discovery of chemical probes, drugs or immunomodulators (R01 Clinical Trial Not Allowed)”

The purpose of this Notice is to correct the instructions for two areas of the Research Strategy in Section IV (Application and Submission Information) of PAR-25-153 “Assay development and screening for discovery of chemical probes, drugs or immunomodulators (R01 Clinical Trial Not Allowed)”.

Section IV. Application and Submission Information

Part 2. Content and Form of Application Submission 

Research Plan

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Research Strategy: Applicants should address the following topics as they pertain to the proposed research project:

Importance of the Research (Significance and Innovation): Applicants should address why the chosen target or pathway is significant for the proposed chemical probe/drug discovery project, and whether the probe will provide new insight into important cancer targets and processes. Preliminary data or published information

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Synopsis

Build and Broaden (B2) supports fundamental research and research capacity across disciplines at minority-serving institutions (MSIs) and encourages research collaborations with scholars at MSIs. Growing the science, technology, engineering and mathematics (STEM) workforce is a national priority. National forecasts of the impending shortage of workers with science and engineering skills and essential research workers underscore a need to expand opportunities to participate in STEM research (President’s Council of Advisors on Science and Technology, 2012).

MSIs make considerable contributions to educating and training science leaders for U.S. economic growth and competitiveness. Yet NSF has received comparatively few grant submissions from, or involving, scholars at MSIs. Targeted outreach activities reveal that MSIs have varying degrees of familiarity with funding opportunities within NSF and particularly within the Social, Behavioral and Economic (SBE) Sciences Directorate. As a result, NSF is limited in its ability to support research

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Notice of Participation of the National Institute of Nursing Research (NINR) in PAR-25-292, “The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)”

This Notice is to inform applicants that the National Institute of Nursing Research (NINR) has joined the Notice of Funding Opportunity (NOFO) PAR-25-292, “The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional), effective for application due dates on or after March 05, 2025.”

The following sections of PAR-25-292 have been revised to reflect the participation of NINR in this NOFO (changes shown in bold italics): 

Part 1. Overview Information

Components of Participating Organizations

National Institute on Minority Health and Health Disparities (NIMHD)

National Institute on Drug Abuse (NIDA)

National Institute of Mental Health (NIMH)

National Cancer Institute (NCI)

National Institute on Aging (NIA) December 06, 2024 – Participation added (NOT-AG-24-088)

National Institute of Nursing

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