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NSF 25-014

October 28, 2024

Dear Colleagues:

The rapid environmental changes currently underway create unprecedented challenges for nearly all life on earth, underscoring an imminent need for understanding organismal resilience in the face of those challenges. The Division of Integrative Organismal Systems’ (IOS) Organismal Response to Climate Change (ORCC) solicitation supports interdisciplinary research on mechanisms of organismal response to climate change that are contextualized through both an eco-evolutionary lens and a plan for use-inspired applications to better predict and mitigate the effects of a rapidly changing climate on earth’s living systems. Critical to those efforts are microorganisms, including bacteria, archaea, fungi, protists, and viruses. Whether free-living, or through partnerships with a diversity of hosts (e.g. other microorganisms, plants, or animals), microorganisms are ubiquitous, diverse, and functionally significant, persisting in spaces that undergo extreme

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